A phase rule footnote

A footnote on allostery.

A manuscript on allostery signed by Francis Crick and Jeffries Wyman was sent by Crick to Jacques Monod in 1965. Monod transmitted a copy of the manuscript, upon which he had written several comments, to Jean-Pierre Changeux, then a post-doctoral fellow at the University of California Berkeley in the laboratory of Howard Schachman. Changeux provided a copy to Stuart Edelstein, a graduate studen...

A footnote on local compactness

A standard example of an impredicative definition is that of the way-below relation [11], and thus of local compactness in (point-free) topology [6]. Local compactness can be dealt with predicatively as in [8], [5]; the particularly convenient re-formulation to be presented is based on a recent result by Peter Aczel [2], and on the observation that, in set-presented topologies, the way-below re...

The Footnote

A Footnote to the Evolution of Digits

Half a billion years ago, the first fourlegged land animal crawled out of the sea onto dry land. How did the limbs that creature crawled on evolve from the fins of its fishy ancestors? This question has long intrigued biologists. Fossil records suggest that tetrapod legs evolved step by step from fins, and comparative gene expression studies have provided some insights into how mutation and nat...

A historical footnote to respiratory therapy.

1 Jackson C, Jackson CL. Diseases of the air and food passages of foreign body origin. Philadelphia: WB Saunders Co, 1936 2 Limper AH, Prakash UBS. Tracheobronchial foreign bodies in adults. Ann Intern Med 1990; 112:604-09 3 Volpe BT, Brandstetter RD. Delayed pneumonia after aspiration of”dashboard” fragment. J Trauma 1985; 25:1173-74 4 Lillington GA, Ruhe BA, Peirce TH, Gorin All. Removal of e...